Research @ CMM
The focus of CMM research has since the beginning been common and currently chronic diseases. Many of these diseases, including rheumatic diseases, psoriasis, MS, cardiovascular diseases and neuropsychiatric diseases such as depression and drug addiction can today be studied and understood using a combination of clinical investigation and modern bioscience present at CMM.
Sweden´s health care system, CMM:s proximity to the clinical care units and its equal proximity to basic science units at Karolinska Institutet have created an internationally unique opportunity to understand the origins, diseases mechanisms and outcomes of these diseases, and thus also new opportunities to develop prevention and targeted therapies. Our strategy is also to combine competence from the 28 research groups of CMM to foster interdisciplinary research, for example regarding understanding of how inflammation may lead to cardiovascular disease (a Linnaeus center embedded in CMM is studying this problem) and how the immune system interacts with the brain.
Research Areas
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Inflammatory diseases include rheumatic diseases, psoriasis and multiple sclerosis as well as other disease where the immune system inadvertently causes chronic inflammation and loss of functions. New therapies are currently revolutionising the care of these diseases, and CMM is in the forefront in the development and use of such therapies.
Research Groups
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Cardiovascular diseases include ischemic heart disease, stroke as well as a number of conditions caused by disturbed functions in our blood vessels. These diseases are among the most common in all populations in the world, and CMM scientists are today world leading in creating improved understanding of why these diseases occur, and how they can be prevented.
Research Groups
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Genetic diseases, encompasses studies of a number of diseases with a very strong genetic component. Different forms of cancers, malformation diseases, diseases of the endocrine system and myopathies are included. Defining the underlying genetic defects and the way that they results in disease impacts both disease prevention strategies as well as care.
Research Groups
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Neuropsychiatric diseases, like depression, drug addiction and others are serious and debilitating conditions where genetic predispostition in combination with environmental factors form the underlying cause of disease devlopment. The understanding of their background and the mechanisms involved can today be turned into efficient therapies and preventive strategies.
Research Groups