Cardiovascular and Metabolic Diseases
The focus is to understand both triggering factors (environmental and genetic) and molecular mechanisms that cause cardiovascular diseases such as ischemic heart attacks and stroke. In addition active research is conducted on the development of new innovative therapies for these diseases.
Groups
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This research group focuses on discovering mechanisms underlying obstruction or weakening of blood vessels leading to life-threatening diseases such as myocardial infarction and aneurysm formation, and at improving diagnosis, prevention and treatment of these conditions.
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Networks of genes are sensing environmental and genetic perturbations and cause coronary artery disease (CAD). We disclose these networks through a combination of clinical genomics and model systems studies of atherosclerosis.
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Our research group focuses on understanding CMV pathogenesis and DNA damage response pathways in inflammation and cancer with a future goal to improve patient diagnosis, prevention and treatment of inflammatory diseases and cancer.
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Very interesting stuff all the time
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In the Experimental Cardiovascular Group we study the connection between cardiovascular diseases and the immune system. Previous studies have shown that activated immune cells play an important role at the development of atherosclerosis. Our aim is to develop new treatments for people with cardiovascular diseases caused by the immune system.
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In the Molecular Endocrinology group we seek to understand how hormones, cytokines and differentiation related signals influence diabetes, growth related disorders and immunological disorders. We are focused on both assembling a systematic view of cell signalling as well as dissecting signalling pathways on a molecular level and to identify biomarkers for disease in order to improve therapy.
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Our research is focused on basic mechanisms both in the development of vascular disease as well as in the response of the vessel wall to vascular interventions for limb ischemia, carotid disease and stroke and aneurysms.