Cancer Genetics

Families undergoing genetic counseling for an increased risk of cancer and where no disease gene is known are being included in our ongoing studies. We have performed many studies to rule out possible candidate genes. Families without known mutations have been recruited to our linkage and association studies. We have in total identified more than 1000 families without mutations in known genes and many of those families have been included in studies. We have ongoing studies in familial colorectal cancer and familial breast cancer and we are looking for new cancer syndromes. We also use large clinical materials for testing the hypothesis of cancer as a complex disease. Our results are implemented into clinical praxis. We have studied effects of genetic counseling and genetic testing and surveillance in cancer families and been able to demonstrate the usefulness of oncogenetic counseling and that it does not bring unwanted side effects of anxiety. We have also continued to improve the procedure of genetic cancer counseling, and to improve the procedure of genetic testing and to evaluate the surveillance program. We have also found that patients under surveillance tolerate this well and are aware of its importance.

For more information, you can also read the Feature Story about our research.

Donations

If you would like to support the research field of your interest this can be done from Sweden by using the following accounts: 
PG 900295-7           BG 900-2957

If you are outside of Sweden, please use the following information:
Bank: SEB, Stockholm, Sweden
Account No. 5201 111 37 012
Iban-numberSE1650000000052011137012
Bic-code: (the bank´s electronic address)ESSESESS
Account holder: Center for Molecular Medicine Foundation L8:05, Karolinska University Hospital171 76 Stockholm, Sweden

Don't forget to mark your payment with the disease, research group or individual researcher that you would like to fund.