Neurogenetics
Vi utför forskning inom en mängd olika områden, såsom, kronisk njursjukdom, aptitkontroll och ätstörningar samt olika psykiatriska sjukdomar som depression, bipolär sjukdom och schizofreni.
We focus on understanding how genes and environment contribute to development and treatment of psychiatric disorders such as depression, bipolar disease, schizophrenia and anorexia. We also focus on the anorectic state that is sometimes observed in end state renal disease, often in combination with cardiovascular complications and inflammation. Several projects are available in this area. Projects typically involve large clinical cohorts that are studied with state of the art molecular methodology, often relating genetic data to disease as well as analyzing how the environment including early experiences may interact with the genetic makeup. Areas of interest that are particularly new and exciting include epigenetic studies as well as inflammation as a factor in psychiatric illness.
Group publications link to Google Scholar
Research Teams
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Our long term goal is to identify susceptibility genes for bipolar disorder and schizophrenia. We also aim at studying the function of these genetic loci.
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Our group has two research lines: we search for genetic, epigenetic and environmental factors that contribute to vulnerability for depression and we investigate if the cold virus adenovirus-36 can be a partial cause of overweight/obesity in Sweden.
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We are studying metabolic, genetic and clinical aspects of psychosis in large Swedish cohorts that are followed prospectively. The use of state of the art epidemiological lab and genetic investigations are combined with studies of other cohorts (diabetes etc) to better understand the massive metabolic complications that accompany psychosis.
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Our group focus on how the hypothalamus of the brain regulates appetite and food intake.
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Identification of genetic and epigenetic factors behind chronic kidney disease and its complications
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What do we do? Establishing mass spectrometric imaging as a mainstream research method in medicine. Using this method to study lipid abnormalities directly at the relevant cells in tissue in Alzheimer’s disease and disorders of metabolism.
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With experiences from two decades of running a core facility, we have accumulated knowledge and proficiency in how to perform services, supervise and support the users. We offer different service levels of genetic analysis, covering DNA sequencing, expression analysis and genotyping, as well as epigenetic analysis.