Publications - CMM

Karolinska Institutet/Karolinska University Hospital

Improved immune responses in mice using the novel chitosan adjuvant ViscoGel, with a Haemophilus influenzae type b glycoconjugate vaccine.
Article

Neimert-Andersson T, Hällgren AC, Andersson M, Langebäck J, Zettergren L, Nilsen-Nygaard J, Draget KI, van Hage M, Lindberg A, Gafvelin G, Grönlund H.
T Cell-Based Therapies For Atherosclerosis.
Curr Pharm Des. 2013 Feb 15. Article

Ketelhuth DF, Gisterå A, Johansson DK, Hansson GK.
Lack of Invariant Natural Killer T Cells Affects Lipid Metabolism in Adipose Tissue of Diet-Induced Obese Mice.
Arterioscler Thromb Vasc Biol. 2013 Mar 21. Article

Strodthoff D, Lundberg AM, Agardh HE, Ketelhuth DF, Paulsson-Berne G, Arner P, Hansson GK, Gerdes N.
Depletion of FOXP3+ regulatory T cells promotes hypercholesterolemia and atherosclerosis
J Clin Invest. 2013; 123(3):1323-34. Article

Klingenberg R, Gerdes N, Badeau RM, Gisterå A, Strodthoff D, Ketelhuth DF, Lundberg AM, Rudling M, Nilsson SK, Olivecrona G, Zoller S, Lohmann C, Lüscher TF, Jauhiainen M, Sparwasser T, Hansson GK.
Diagnostic profile and suicide risk in schizophrenia spectrum disorder
Schizophr Res. 2010 Nov;123(2-3):251-6. doi: 10.1016/j.schres.2010.07.014. Epub 2010 Aug 7 Article

Reutfors J, Bahmanyar S, Jönsson EG, Ekbom A, Nordström P, Brandt L, Ösby U
Increased plasma levels of thioredoxin-1 in patients with first episode psychosis and long-term schizophrenia
Prog Neuropsychopharmacol Biol Psychiatry. 2011 Jun 1;35(4):1117-21. doi: 10.1016/j.pnpbp.2011.03.012. Epub 2011 Mar 30. Article

Owe-Larsson B, Ekdahl K, Edbom T, Osby U, Karlsson H, Lundberg C, Lundberg M
Carriers of the UGT1A4 142T>G gene variant are predisposed to reduced olanzapine exposure--an impact similar to male gender or smoking in schizophrenic patients
Eur J Clin Pharmacol. 2010 May;66(5):465-74. doi: 10.1007/s00228-009-0783-8. Epub 2010 Feb 9 Article

Ghotbi R, Mannheimer B, Aklillu E, Suda A, Bertilsson L, Eliasson E, Osby U.
Mortality and causes of death in schizophrenia in Stockholm county, Sweden
Schizophr Res. 2000 Sep 29;45(1-2):21-8. Article

Osby U, Correia N, Brandt L, Ekbom A, Sparén P.
Increased expression of pro-inflammatory genes in abdominal subcutaneous fat in advanced chronic kidney disease patients
J Intern Med. Apr;269(4):410-9. 2011 Article

Witasp A, Carrero JJ, Heimbürger O, Lindholm B, Hammarqvist F, Stenvinkel P, Nordfors L.
Genetic studies in chronic kidney disease: basic concepts
J Nephrol. 2012 Mar-Apr;25(2):141-9. doi: 10.5301/jn.5000145. Article

Nordfors L, Luttropp K, Carrero JJ, Witasp A, Stenvinkel P, Lindholm B, Schalling M
Genetic studies in chronic kidney disease: interpretation and clinical applicability
J Nephrol. 2012 Nov-Dec;25(6):851-64. doi: 10.5301/jn.5000216 Article

Witasp A, Nordfors L, Carrero JJ, Luttropp K, Lindholm B, Schalling M, Stenvinkel P.
Physical activity is associated with decreased global DNA methylation in Swedish older individuals
Scand J Clin Lab Invest. 2013 Mar;73(2):184-5. doi: 10.3109/00365513.2012.743166. Epub 2012 Nov 22. Article

Luttropp K, Nordfors L, Ekström TJ, Lind L
Carbamazepine protects against megencephaly and abnormal expression of BDNF and Nogo signaling components in the mceph/mceph mouse
Neurobiol Dis. 2006 Nov;24(2):374-83. Epub 2006 Sep 20 Article

Lavebratt C, Trifunovski A, Persson AS, Wang FH, Klason T, Ohman I, Josephsson A, Olson L, Spenger C, Schalling M.
Common neuropeptide Y2 receptor gene variant is protective against obesity among Swedish men
Int J Obes (Lond). 2006 Mar;30(3):453-9 Article

Lavebratt C, Alpman A, Persson B, Arner P, Hoffstedt J.
Single nucleotide polymorphism (SNP) allele frequency estimation in DNA pools using Pyrosequencing
Nat Protoc. 2006;1(6):2573-82. Article

Lavebratt C, Sengul S.
Lack of potassium channel induces proliferation and survival causing increased neurogenesis and two-fold hippocampus enlargement
Hippocampus. 2007;17(4):292-304 Article

Almgren M, Persson AS, Fenghua C, Witgen BM, Schalling M, Nyengaard JR, Lavebratt C.
Title: Depression: Genetic, epigenetic and DNA biobank studies
Dissertation
Title: Gene-environment factors in depressive disorders with a focus on circadian genes
Dissertation
Title: Neural growth - with special emphasis on adult neurogenesis and the effect of antiepileptic drugs
Dissertation
Title: The megencephaly mouse – from gene to neuronal proliferation
Dissertation
Title: Genetic factors influencing susceptibility to intracellular infections
Dissertation
Title: Megencephaly, significance, biology and identification of a genetic cause
Dissertation
Kv1.1 channels act as mechanical brake in the senses of touch and pain
Neuron. 2013 Mar 6;77(5):899-914. doi: 10.1016/j.neuron.2012.12.035 Article

Hao J, Padilla F, Dandonneau M, Lavebratt C, Lesage F, Noël J, Delmas P
Dog saliva - an important source of dog allergens
Allergy 2013 Mar 7 Article

Polovic N, Wadén K, Binnmyr J, Hamsten C, Grönneberg R, Palmberg C, Milcic-Matic N, Bergman T, Grönlund H, van Hage M.
The KMO allele encoding Arg452 is associated with psychotic features in bipolar disorder type 1, and with increased CSF KYNA level and reduced KMO expression
Molecular Psychiatry advance online publication 5 March 2013; doi: 10.1038/mp.2013.11 Article

C Lavebratt^1,2, S Olsson³, L Backlund⁴, L Frisén^1,2,4, C Sellgren⁵, L Priebe^6,7, P Nikamo^2,3, L Träskman-Bendz⁸, S Cichon^6,7,9, M P Vawter¹⁰, U Ösby^1,2,11, G Engberg³, M Landén^5,12, S Erhardt³ and M Schalling^1,2
The KMO allele encoding Arg452 is associated with psychotic features in bipolar disorder type 1, and with increased CSF KYNA level and reduced KMO expression
Molecular Psychiatry advance online publication 5 March 2013; doi: 10.1038/mp.2013.11 Article

C Lavebratt^1,2, S Olsson³, L Backlund⁴, L Frisén^1,2,4, C Sellgren⁵, L Priebe^6,7, P Nikamo^2,3, L Träskman-Bendz⁸, S Cichon^6,7,9, M P Vawter¹⁰, U Ösby^1,2,11, G Engberg³, M Landén^5,12, S Erhardt³ and M Schalling^1,2
Genetic and epigenetic associations of MAOA and NR3C1 with depression and childhood adversities
Int J Neuropsychopharmacol. 2013 Mar 1:1-16. Article

Melas PA, Wei Y, Wong CC, Sjöholm LK, Aberg E, Mill J, Schalling M, Forsell Y, Lavebratt C.

Link to PubMed
CRY2 is associated with depression
PLoS One. 2010 Feb 24;5(2):e9407. doi: 10.1371/journal.pone.0009407 Article

Lavebratt C, Sjöholm LK, Soronen P, Paunio T, Vawter MP, Bunney WE, Adolfsson R, Forsell Y, Wu JC, Kelsoe JR, Partonen T, Schalling M.

Link to PubMed
CRY2 is associated with rapid cycling in bipolar disorder patients
PLoS One. 2010 Sep 9;5(9):e12632. doi: 10.1371/journal.pone.0012632 Article

Sjöholm LK, Backlund L, Cheteh EH, Ek IR, Frisén L, Schalling M, Osby U, Lavebratt C, Nikamo P.

Link to PubMed
Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4
Nat Genet. 2011 Sep 18;43(10):977-83. doi: 10.1038/ng.943 Article

Psychiatric GWAS Consortium Bipolar Disorder Working Group.

Link to PubMed

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