Malformation genetics

” About 2 % of all children are born with a malformation. Our research focus on identifying different factors, environmental and genetic, that cause congenital malformations. Studying malformations increase our knowledge about foetal development and help us to optimize the treatment and improve the quality of life for the patients. Hypospadia, an abnormally placed urinary opening, […] ”

Clinical Genetics

Magnus Nordenskjöld

Magnus Nordenskjöld
Professor, MD

” CANCER GENETICS We try to understand why patients with apparently identical forms of cancer show different course of the disease. We study chromosome aberrations and gene expression in different types of cancer cells. Studies of the rare recessive Familial Hemophagocytic Lymphohistiocytosis (FHL) outlines mutations in known disease genes and tries to identify “new” genes for […] ”

+46 8 517 739 28

Cancer genetics

Annika Lindblom_1

Annika Lindblom

”   Families undergoing genetic counseling for an increased risk of cancer and where no disease gene is known are being included in our ongoing studies. We have performed many studies to rule out possible candidate genes. Families without known mutations have been recruited to our linkage and association studies. We have in total identified more […] ”

+46 8 517 752 48
L8:02 room 39

Myopathy research


Thomas Sejersen

” Approximately 1 in 1000 persons in Sweden suffer from a neuromuscular disorder. Most of these are hereditary, Several muscle diorders also affect the heart and cause cardiomyopathy. The aim of our research is to increase the knowledge of disease causing mechanisms in muscle disorders and cardiomyopathies, and to improve diagnosis and treatment of them. Our […] ”

+46 8 517 739 20

Multiple sclerosis (MS)

JanHillert kopia

Jan Hillert
Professor, MD

” Multiple sclerosis, commonly known as MS, is a chronic inflammatory disease of the central nervous system which, if left untreated, causes increasing disability for over one million people worldwide. MS treatments are so far partially effective or hampered by side effects, leaving a great clinical need for intensified research on disease mechanisms and novel therapeutics. […] ”

+46 8 517 769 73, +46 8 517 760 97

Cardiovascular genetics & genomics

Per Eriksson_KI

Per Eriksson

” The mission of the group is to unravel the etiology and pathophysiological mechanism underlying atherosclerosis, arterial thrombosis and aneurysm formation. This is pursued by a combination of physiological, biochemical and molecular genetics and genomics studies in vivo in humans and in model systems as well as functional molecular genetic studies in in vitro and ex […] ”

+46 8 5177 32 02


Martin Schalling

Martin Schalling

” We focus on understanding how genes and environment contribute to development and treatment of psychiatric disorders such as depression, bipolar disease, schizophrenia and anorexia. We also focus on the anorectic state that is sometimes observed in end state renal disease, often in combination with cardiovascular complications and inflammation. Several projects are available in this area. […] ”

+46 8 517 744 81

Sarcoidosis - Grunewald

johan grunewald_3_beskuren

Johan Grunewald
MD, Professor

” Sarcoidosis is a pulmonary inflammatory disease of unknown etiology, affecting young middle aged people, with about 2000 new cases yearly in Sweden. 50-100 new sarcoidosis patients are investigated yearly with bronchoscopy and bronchoalveolar lavage (BAL), giving us access to cells at the focus of inflammation. Typically, there is an accumulation of Th1 cells to the […] ”

+46 08 517 751 17

Genetics of rheumatic and other inflammatory diseases - Padyukov


Leonid Padyukov

”   Human complex diseases characterized by involvement of both environmental and genetic factors with important contribution from gene-gene and gene-environmental interaction. The pathways of most of diseases of this type are influenced through immunological mechanisms, e.g. inflammation. We like to understand how genetic variations influence development and/or protection from human common complex inflammatory diseases. To […] ”

+46 8 517 756 60



Ingrid Kockum

” The Multifactorial disease genetics team conducts genetic epidemiology of multifactorial diseases, that is diseases that are caused by an interplay between several genetic and environmental factors. The focus of the group is genetics of autoimmune diseases such as type 1 diabetes and multiple sclerosis. The goal is to identify genetic and environmental risk factors and […] ”

+46 8 517 700 00

Depression - Lavebratt-Holmqvist

Catharina Lavebratt och Martin Schalling på CMM

Catharina Lavebratt-Holmqvist
Associate Professor

” Depression is common and an important cause of morbidity and mortality worldwide and a majority of the affected persons remain untreated. The one-year prevalence of depression is reported to be 5-10% and the incidence is increasing, especially in younger age groups. Both environment, such as negative life events and socioeconomic conditions, as well as heritable […] ”

+46 517 765 24

CMM Research Groups




Cardiovascular and Metabolic Diseases