Asset Publisher

Molecular puzzle reveals unknown stages of fetal development

Molecular puzzle reveals unknown stages of fetal development

By applying gene analysis to individual cells from early mouse embryos, CMM researcher Qiaolin Deng and her team have discovered previously unknown cellular stages of fetal development from fertilized egg to living being.

Dr. Qiaolin Deng led the study which has revealed new details of the critical phase between the attachment of the embryo to the uterus and the formation of the first anatomical axis, at which point the embryonic cells begin their journey towards creating a body, with a front and a back.

“The study has revealed previously unknown details about what happens before the early embryo gains its first spatial orientation, and shown that the cells along the future head-tail axis have different differentiation potential,” says Dr. Deng to KI News.

Qiaolin Deng

Qiaolin Deng. Photo: private

 

The study Single-cell RNA-seq reveals cellular heterogeneity of pluripotency transition and X-chromosome dynamics during early mouse development is published in the scientific journal Cell Reports.

Read the full news story at Karolinska Institutet website.

NEWS

Ning Xu Landén 2020 year’s winner of the LEO Foundation Award

Ning Xu Landén 2020 year’s winner of the LEO Foundation Award Associate Professor Ning Xu Landén, Group Leader at CMM is the winner of this year’s LEO Foundation Award in Region EMEA...

Nils Landegren receives ERC Starting Grant for studying sex differences in the human immune system

Nils Landegren receives ERC Starting Grant for studying sex differences in the human immune system Photo: Hans Ericksson, SSMF Nils Landegren , Researcher at CMM, has been awarded...

Verification project of SARS-CoV-2 antibody tests receives funding from Swelife

Verification project of SARS-CoV-2 antibody tests receives funding from Swelife Photo: Mattias Bronge, Karolinska Institutet A validation project of new SARS-CoV-2 antibody tests,...

Grant to Qiaolin Deng for the single-cell technology core at CMM

Grant to Qiaolin Deng for the single-cell technology core at CMM Qiaolin Deng, private photo We congratulate Associate Professor and CMM Team Leader Qiaolin Deng who received a SFO...

Identification of key gene for improvement of multiple sclerosis treatments

Identification of key gene for improvement of multiple sclerosis treatments Karl Carlström and Fredirk Piehl. Photo: Stefan Zimmermann   CMM researcher Karl Carlström and...

Sweden’s innovation agency Vinnova extends the funding of Genomic Medicine Sweden with additional SEK 36 million

Sweden’s innovation agency Vinnova extends the funding of Genomic Medicine Sweden with additional SEK 36 million Sweden’s innovation agency Vinnova extends the funding of the national...

The Swedish Heart-Lung Foundation major grant 2020 goes to Marie Wahren-Herlenius

The Swedish Heart-Lung Foundation major grant 2020 goes to Marie Wahren-Herlenius Professor Marie Wahren-Herlenius, Group Leader at CMM, has received the biggest yearly grant in Sweden...

Simple blood test may help predict MS progression, study finds

Simple blood test may help predict MS progression, study finds Photo: Ali Manouchehrinia   A study led by the CMM researchers Ali Manouchehrinia (first...

Experimental study finds new substances with higher specificity and therapeutic potential in multiple sclerosis

Experimental study finds new substances with higher specificity and therapeutic potential in multiple sclerosis   Karl Carlström, photo Stefan Zimmerman   Karl...

Early exposure to cannabis boosts young brains' sensitivity to cocaine, rodent study shows

Early exposure to cannabis boosts young brains' sensitivity to cocaine, rodent study shows A study made by Philippe Melas from Karolinska Institutet together with colleagues at Columbia...