Grants

Grants

2018

The following CMM researchers have received Swedish Research Council (VR) Funding 2018 (amounts in SEK)

Research project grants within medicine and health

Maja Jagodic

2019: 1 600 000     2020: 1 000 000     2021: 1 000 000     2022: 1 200 000

Project title: Epigenetik i Multipel skleros: mot en bättre förståelse av patogena mekanismer och en förbättrad sjukdomshantering.

Qiaolin Deng

2019: 1 600 000     2020: 1 000 000     2021: 1 000 000     2022: 1 200 000

Project title: Mot den nästa generationen – en bättre kunskap om könsceller och könscellstumörer hos däggdjur.

Dawei Xu

2019: 1 200 000     2020: 1 200 000     2021: 1 200 000     2022: 1 200 000

Project title: m6A RNA metylering kontrollerar telomerhomeostas: Implikationer vid åldrande och oncogenes.

Jan Hillert

2019: 1 200 000     2020: 1 200 000     2021: 1 200 000

Project title: Individualiserad behandling av multipel skleros på riktigt – att långsiktigt förhindra försämring.

Helena Erlandsson Harris

2019: 800 000     2020: 800 000     2021: 800 000

Project title: Studier av inflammation, smärta och destruktion vid artrit, med särskilt fokus på alarminet HMGB1.

Robert Harris

2019: 800 000     2020: 800 000     2021: 800 000

Project title: Nya immunointerventioner för progressiva neurologiska sjukdomar – att bota den obotliga?

Ann Nordgren

2019: 800 000     2020: 800 000     2021: 800 000

Project title: Medfödda genetiska faktorers betydelse för barncancer.

Leonid Padyukov

2019: 800 000     2020: 800 000     2021: 800 000

Project title: Genetik interaktion vid autoimmuna sjukdomar.

Eduardo Villablanca

2019: 800 000     2020: 800 000     2021: 800 000

Project title: Reglering av tarmbarriärens funktion via diet-deriverade kärnreceptor ligander.

Anna Färnert

2019: 800 000     2020: 800 000     2021: 800 000

Project title: Hur blir och förblir man immun mot malaria?

 

Proof of concept within life sciences

Anna Färnert

2019: 950 000

Project title: Nya metoder för att studera antigenspecifika immunsvar.

 

Grant of employment as half-time researcher in a clinical environment

Jakob Wikström

2019: 1 850 000     2020: 1 850 000     2021: 1 850 000

Project title: Endoplasmatiskt nätverk stress i kroniska bensår: en ny behandlingsstrategi?

 

Starting grant – medicine and health

Muhammad Asghar

2019: 1 500 000     2020: 1 500 000     2021: 1 500 000     2022: 1 500 000

Project title: Åldrande: Långtidseffekter av tidigare infektioner.

 

The following CMM researchers have received ALF Funding 2018 (amounts in SEK)

Marie Wahren-Herlenius      

2019: 1 000 000     2020: 1 000 000     2021: 1 000 000

Project title: Sjögrens syndrom – kliniska och patogenetiska studier.

Per Eriksson

2019: 800 000     2020: 800 000     2021: 700 000

Project title: Patogenes vid aortaaneurysm.

Anna Färnert

2019: 700 000     2020: 700 000     2021: 600 000

Project title: Hur blir och förblir man immun mot malaria: kliniska och immunologiska studier av malaria hos resenärer och migranter.

Johan Grunewald

2019: 650 000     2020: 700 000     2021: 500 000 

Project title: Identification of the disease causing agent in pulmonary sarcoidosis in order to improve therapy and clinical management.

Peder Olofsson

2019: 650 000     2020: 700 000     2021: 500 000

Project title: Vascular Inflammation and Atherosclerosis – Clinical and Experimental Studies.

Tomas Olsson                            

2019: 800 000     2020: 800 000

Project title: Multipel skleros: tvärdisciplinära studier av orsaker, patogenes och behandlingsstrategier.

Annika Lindblom

2019: 700 000     2020: 700 000

Project title: Cancer predisposition, prediktion och prevention.

Jakob Wikström                        

2019: 400 000     2020: 400 000

Project title: Darier’s disease: Identification of novel treatments for a severe skin disorder through a patient derived screening assay.

Agneta Nordenskjöld 

2019: 650 000

Project title: Molekylära och kliniska studier av medfödda missbildningar.

Jon Lampa

2019: 400 000

Project title: Kartläggning av smärtmönster vid reumatoid artrit – förekomst, centralnervösa smärtmekanismer och relation till antireumatisk behandling.

Lou Brundin 

2019: 300 000

Project title: Allvarlig neuroinflammation; studier av Neuromylelitis Optica och neurosarkoidos.

 

KI funds and foundations

Afsar Rahbar: 217 400 SEK

Ali Manouchehrinia: 225 000 SEK

Lara Kular: 206 800 SEK

Susanna Brauner: 184 000 SEK

Majid Pahlevan Kakhki: 85 000 SEK

 

Ljubica Matic has been awarded the Hagberg Prize for 2018 by the Board of Sven and Ebba-Christina Hagbergs Foundation. The Hagberg Prize comes with a personal prize of 150 000 SEK and a research grant of 275 000 SEK

Muhammad Asghar has been appointed Ragnar Söderberg Fellow in Medicine 2018. The money grant is a total of 8 million SEK over a period of five years.

John Pernow has received a research grant of € 90 000 from European Association for the Study of Diabetes for the project The novel role of red blood cells in development of macrovascular complications in tpe 2 diabetes.

Karin Loré has received a grant from the the Bill and Melinda Gates Foundation. The total amount of the grant is 1.4 million US dollar including 0.37 million US dollar to one subcontractor in Germany over 20 months.

Mats A A Persson has been awarded an Exploratory pre-Seed grant of DKK 500 000 by the Novo Nordisk Foundation.

Olle Kämpe and Nils Landegren received a grant of DKK 3 Million from the Novo Nordisk Foundation.

Marie Wahren Herlenius group has, as partners, received a IMI2 EU grant of € 15,4 Million for the NECESSITY Project (NEw Clinical Endpoints in primary Sjögren’s Syndrome: an Interventional Trial based on stratifYing patients). Partners within the project are from several European countries including France (coordination), Norway, England, The Netherlands, Spain, Greece and Italy.

Majid Pahlevan Kakhki have recently received MSIF/ECTRIMS McDonald Fellowship from Multiple Sclerosis International Federation. The fellowship consists of a two-year grant, around 750 000 SEK to work on the project entitled Epigenetics approach to understand mechanisms underpinning disease progression in Multiple Sclerosis. 

ENDpoiNTs (Novel Testing Strategies for Endocrine Disruptors in the Context of Developmental NeuroToxicity) is an EU Horizon-2020 research and innovation action that has just been granted 6.89 million, which Joëlle Rüegg will be coordinating 2019-2023. It includes 14 partners from within Europe, the US and Australia.

Martin Schalling, Ida AK Nilsson and Annika Eriksson have received 9 million SEK from KI/SLL Core, for KIGene to develop Spatial Transcriptomics.

 

CMM researchers who received a grant of 500.000 SEK each from Hjärnfonden are

Tomas Ekström, for the project Genetics and epigenetics in alcohol abuse; implications for vulnerability and therapy.

Catharina Lavebratt, for the project ADHD hos barn och vuxna: tarmflorans påverkan på hjärnan ger nya behandlings-möjligheter?

Ida AK Nilsson, for the project Neurodegeneration and -inflammation in Anorexia Nervosa.

Martin Schalling, for the project Predicting therapeutic success in bipolar disorder using patient-derived induced pluripotent stem cells - Discovery and validation of biomarkers.

Per Svenningsson for the project Saposin C och GPR37 som läkemedelsmåltavlor och biomarkörer vid Parkinsons sjukdom.

Maja Jagodic for the project Tillämpad epigenetik: etiologi och bättre behandlingar vid Multipel Skleros.

Jan Hillert for the project Personalized medicine in multiple sclerosis – to optimize long-term outcome.

 

Two post-docs from Kristina Broliden lab have received a research grant of SEK 100 000 each from the Swedish Physicians against AIDS Research Foundation ("Läkare mot AIDS" Forskningsfond):

Gökçe Günaydın for the project A novel concept for safety evaluation of local prophylactic compounds against HIV infection.

Anna Gibbs for the project MAIT cells-local controllers of HIV mucosal infection?

 

Ulf Hedin and Ljubica Matic have received the Heart-Lung Foundations Great Research Grant 2018 of 15 million SEK. The great research grant is awarded annually, and is the largest individual grant by the Heart Lung Foundation to create the conditions for a crucial research breakthrough.

Jesper Tegnér has as co applicant received Wallenberg Project grant of 36.8 million SEK over five years for the project The Achilles’ heel of breast cancer. Main applicant is Dr. Anita Göndör, Karolinska Institutet and the other co-applicants are Jonas Bergh, Lars Holmgren and Rolf Olsson.

Helena Idborg and Susanne Gräslund have been granted 100 000 SEK from Reumatikerförbundet for the project Characterization and validation of IRF5 and other biomarkers to identify SLE patients suitable for a tailored treatment. An earlier study has preliminary identified IRF5 and a selected few other proteins as potential biomarkers for SLE. This project aims to validate IRF5 in this context. Recombinant antibodies for IRF5 have already been made within the ULTRA-DD project and will now be used in IP-MS to detect the presence of IRF5 in circulation of SLE patients compared to healthy controls.

 

The following CMM researchers have received research grants from King Gustaf V’s and Queen Victoria’s Order of Freemasons for the year 2018
Magnus Bäck Studies of the inflammatory process in atherosclerosis and aorta stenosis

Anca Catrina Studies of joint inflammation and bone destruction and prevention of joint diseases

Francesco Cosentino Implication of environmental factors for genetic reprogramming as explanation to cardiovascular diseases in overweight and diabetes

Helena Erlandsson Harris Implication of the alarmin HMGB1 for the neuro-inflammatory reaction in stroke and the development of new therapies

Johan Grünewald Implications of T helper cells in sarcoidosis; a model for inflammatory lung diseases

Ingrid Lundberg Implication of the lung in a chronic rheumatic disease characterized of muscle weakness

Per Svenningsson G-protein coupled receptors and their role in Parkinson’s disease

 

Christopher Sundling received a grant from Magnus Bergvalls Stiftelse for 80,000 SEK for investigating atypical B cells in malaria.

Anca Catrina has received a grant from the Swedish research council of 17 000 000 SEK over three years for clinical treatment research.

Lynn Butler has received a research fellowship from the Heart lung foundation, a yearly amount of 924 000 SEK during 2018-2020.

The project Strategic planning for implementation of clinical routine tests of antibodies against biological drugs has received a 3,5MSEK grant from Swelife. The aim of the project is to establish a new routine in clinical care to detect patients who develop anti-drug antibodies making the immune system react against the treatment. By continuous follow-up tests to measure drug levels, the effect of the treatment can be obtained in these patients and make the treatment regimen both more efficient and safe. Project manager is Anna Fogdell-Hahn.

 

2017

The following CMM researchers have received funding from the Swedish Heart Lung foundation
Anders Hamsten 
600 000
Ewa Ehrenborg 300 000
Lynn Butler 1 200 000
Ulf Hedin  2 700 000
Rachel Fisher  900 000
Thomas Renné  1 800 000
Natalia V Rivera Sifaki  900 000
Peder Olofsson  900 000
Francesco Cosentino  900 000
Göran Hansson  3 600 000

Maria Sabater Lleal, PhD, NIH-National Heart, Lung and Blood Institute grant
Principal Investigator: Prof. Nicholas L. Smith (Washington University), Subrecipient Principal Investigator at KI: Maria Sabater Lleal (KI). Total amount at KI: $92,107
Total amount for the project: $708,902

Ida AK Nilsson, PhD, Assistant Professor, ALF Med N grant: Neuroinflammation, neurodegeneration och mitokondriell dysfunktion vid Anorexia Nervosa/ Neuroinflammation, neurodegeneration and mitochondrial dysfunction in Anorexia Nervosa. 300 000 kr annually 2018-2019

Natalia V Rivera has revceived 60,000 kr from the Lisa och Johan Grönbergs Stiftelse  for sarcoidosis research.

Vincent Millischer got 130,000kr through the Stiftelsen Bror Gadelius Minnesfond.

Carlos Villaescusa has received 250.000 SEK from the Åke Wibergs Stiftelsen 2016.

Carlos Villaescusa has received 150.000 SEK from the Åhlén Stiftelsen 2016.

Robert Harris has received a grant of 400 000 SEK  from AlzheimerFonden.

Francesco Cosentino has been granted 200.000 SEK Queen Victoria’s and King Gustav V Foundation to support the research on vascular redox signaling in obesity and diabetes

Michael Hagemann-Jensen has received a grant of 360.000 from MS Forskningsfonden

Magnus Bäck and Anders Franco-Cereceda has been awarded a Clinical Scientist Training Programme (CSTP) grant has been awardedfor the PhD student Oscar Persson.

Magnus Bäck, Jordan Miller and Grace Verzosa have been awarded Karolinska Institutet – Mayo Clinic Travel Award in order to allows a member of the Bäck group to go to the Mayo Clinic in Rochester, Minnesota, USA to train in echocardiography.

Katarina Tengvall has been granted 120 000 SEK from the Swedish MS society

Katarina Tengvall has been granted a two year post doc stipend from the Swedish Brain Foundation

Ljubica Perisic Matic has been granted 924 000 SEK from the Heart Lung Foundation for the project entitled “Clinical and experimental studies in search for markers of atherosclerosis: Mechanisms of plaque rupture governed by smooth muscle cells”

Ulf Hedin, Ljubica Matic and Daniel Ketelhuth has been granted KID funding of 1 400 000 SEK to recruit a PhD student for the project “The role of proprotein convertases in control of smooth muscle cell function and vascular disease”

Ulf Hedin has received, jointly with Professor Christian Gasser at KTH, SEK 1 600 000 SEK from SLL during the period 2017-2018 for the research project “Personalized Vascular Decisions by image-based biomechanics solutions”

Rebecka Hultgren has received SEK 1 260 000 from the Swedish Heart-Lung Foundation for the project: “Aneurysm disease in women and men – development, growth and risk of rupture”.

Rebecka Hultgren has received SEK 600 000 from the Swedish Heart-Lung Foundation for the research project: “Aneurysm disease in women and men – development, growth and risk of rupture”.

Lara Kular has received 300 000 SEK from Åke Wibergs stiftelse

Lara Kular has received 62 500 SEK from Neuroförbundet

Stephen Malin, Hong Jin, John Pernow and Lars Maegdefessel has been granted KID funding of 1 280 000 SEK to recruit a PhD student for the project “Activation of humoral immunity at atherosclerosis initiation and the consequences for plaque rupture”.

Carlos Villaescusa has received 250.000 SEK from the Åke Wibergs Stiftelsen 2016.

Carlos Villaescusa has received 150.000 SEK from the Åhlén Stiftelsen 2016.

Nikolas Herold has received 600 000 SEK form the Swedish Child Cancer Fund for the project” Improved survival for children with AML, T-ALL and T-LBL by reducing resistance to pharmaceutical drugs”

2016

Fredrik Wermeling has been awarded 243 000 SEK from Karolinska Institutet Foundation Grants for Rheumatology Research, title of application: Regulation of the activity of autoantibodies in rheumatic diseases. He has also been granted 150 000 SEK from the foundation Professor Nanna Svartz Fond, title of application: En skyddande effekt av IL-4 vid reumatoid artrit.

Jacob Wikström in the Molecular Dermatology Research Group has received 4 500 000 SEK funding from the Leo Foundation to study mitochondrial function in wound healing.

Stephen Malin received funding from Heart and Lung Foundation, 800,000SEK for 2017+2018

Maria Sabater Lleal and Silvia Aldi got 600,000 SEK from the Heart and Lung Foundation for 2017-2018 for the project: “New genetic risk factors for venous and arterial thrombosis”.

John Pernow received SEK 1 400 000 x 3 years from Heart and Lung Foundation for the project “The importance of endothelial- and erythrocyte dysfunction for cardiovascular complications in type 2 diabetes”

Tomas Ekström has reveiced 2 500 000 SEK of ALF-funding (3 years).

Catharina Lavebratt and Martin Schalling was granted 1 000 000 SEK from the foundation Ekhagastiftelsen for their project ’Microbiota in children and adolescents with neuropsychiatric diseases: a new way of treatment’

Zhichao Zhou received SEK 162 500 from Olaussons Fund Department of Cardiology, Karolinska University Hopsital for the project “The Effect of Red Blood Cells on Endothelial Function in Type 2 Diabetes: Role of Arginase”

Ulf Hedin has received SEK 250 000 from the Mats Kleberg Foundation for research on biomarkers of plaque instability in the carotid artery.

 

The following CMM researchers have received grants from SWElife:

Anna Fogdell Hahn for the project “Setting the clinical threshold level of anti-drug antibodies for TNF-inhibitors.” The sum amounts to 1 000 000 SEK.

Saedis Saevarsdottir for the project “New diagnostic assays and a decision support system for individualized care in rheumatoid arthritis.” The sum amounts to 1 000 000 SEK for the first year.

 

Annelie Tjernlund recieved 112 880 SEK from The Swedish Society of Medicine for the project “In situ analysis of tissue resident memory CD8+ cells mediating potential protection of HIV mucosal infection.”

Annelie Tjernlund recieved 200 000 SEK from the foundation Clas Groschinskys Minnesfond for the project “In situ analysis of tissue resident memory CD8+ cells mediating potential protection of HIV mucosal infection.”

Albert Dahdah recieved 250 000 SEK from Alex and Eva Wallström Foundation for scientific research and education for Arthritis research.

 

The following CMM researchers have received grants 2016 from Konung Gustav V:s och Drottning Victorias Frimurarestiftelse:

Helena Erlandsson Harris 250 000 SEK
Alarminet HMGB1s betydelse för den neuroinflammatoriska reaktionen vid stroke och utarbetande av ny terapi

Göran K Hansson 250 000 SEK
Åderförkalkning, inflammation och immunförsvar

Ingrid Lundberg 200 000 SEK
Lungans betydelse för insjuknande i en kronisk reumatisk sjukdom som leder till svaghet i musklerna

Per Svenningsson 200 000 SEK
G-proteinkopplade receptorer och deras roll vid Parkinsons sjukdom

 

The following CMM researchers have received grants 2016 from Reumatikerfonden:

Ulf Andersson 150 000 SEK
Utarbetande av ny terapi mot kronisk artrit.

Anca Catrina Irinel 150 000 SEK
Kartläggning av sambandet mellan sjukdomsspecifika antikroppar och vävnadsdestruktion vid RA.

Tomas Ekström 100 000 SEK
Epigenetiska undersökningar för att förstå risker och mekanismer vid uppkomst och terapi vid RA

Helena Erlandsson Harris 150 000 SEK
Studier av alarminet HMGB1s roll vid artrit som prognostisk/diagnostisk biomarkör och möjlig målmolekyl för ny terapi.

Caroline Grönwall 100 000 SEK
Autoantikroppsrepertoarer i RA

Iva Gunnarsson 200 000 SEK
SLE – med njurengagemang – biomarkörer och prognos?

Per-Johan Jakobsson 250 000 SEK
Tidig diagnostik och tidig behandling vid reumatisk sjukdom.

Lars Klareskog 300 000 SEK
Nya vägar att förebyggande och behandla RA.

Marina Korotkova 100 000 SEK
Selektiv hämning av mikrosomalt prostaglandin E-syntas 1: effekter på inflammatoriska processer vid reumatiska sjukdomar.

Jon Lampa 75 000 SEK
Kvarstående smärta och trötthet trots antireumatisk behandling, en epidemiologisk och mekanistisk kartläggning vid RA.

Lundberg Ingrid 350 000 SEK
Sjukdomsmekanismer och behandlingseffekter vid kronisk reumatisk muskelinflammation, myosit.

Vivianne Malmström 250 000 SEK
Lymfocyters betydelse vid inflammatorisk reumatisk sjukdom.

Leonid Padyukov 100 000 SEK
Functional genetics of rheumatoid arthritis.

Saedis Saevarsdottir 150 000 kr
Utveckling av ett verktyg för individanpassad behandling av RA – baserat på kliniska variabler, biomarkörer och livsstilsfaktorer.

Louise Sjöholm 75 000 kr
Är Porphyromonas gingivalis roll i RA associerad med en störd mag-tarmhomeostas?

Elisabet Svenungsson 150 000 kr
Kardiovaskulär sjukdom, subfenotyper och sjukdomsaktivitet. – prospektiva studier av SLE och antifosfolipidsyndromet (APS).

Marie Wahren-Herlenius, 250 000 kr
Sjögrens syndrom – kliniska och immunologiska studier.

 

The Swetox (Swedish Toxicology Sciences Research Center) project, EDC-2020, in which Joelle Rüegghas a part received 20 million SEK from FORMAS for two more years.

 

The following CMM researchers have received grants 2015 from Radiumhemmets forskningsfond:

Name Period Amount SEK
Jesper Tegnér 2016-2017 400 000
Molecular analysis of the immunosuppressive tumor microenvironment with special reference to melanoma.

Per-Johan Jakobsson 2016 250 000, 2017 250 000
Immunomodulating functions of prostaglandin E2 in the tumor microenvironment, a novel target for therapeutic intervention.

 

Robert Harris received 600 000 SEK from Alzheimerfonden for the project: “Understanding microglial dysfunction in Alzheimer’s Disease – characterizing pathogenesis and potential for therapy”

Lars Maegdefessel has received a ERC Starting Grant for his project ”Therapeutic and biomarker potential of long non-coding RNAs in vascular disease. The sum amounts to €1.5 million

Fredrik Piehl received a grant from the Vetenskapsrådet for the clinical study: Rituximab for new onset myasthenia gravis; the RINOMAX study: 6 300 000 SEK

Maria Sabater Lleal received a EHA-ISTH joint fellowship: €100,000 for 2 years

Lynn Butler received a grant from Hjärt Lungfonden: ‘Using the endothelial specific proteome to identify new mechanisms of cardiovascular disease’ (2016-2018, 786,000 SEK)

Pernilla Strid received 50 000 SEK from the foundation Lars Hiertas Minne and 53 000 SEK from NHR fonden (Neuroförbundet).

Ida Nilsson has recieved two grants for her research in anorexia:
Thurings stiftelse, 50 000 SEK, Is mitochondrial dysfunction a risk factor for Anorexia Nervosa?
Tore Nilssons stiftelse, 70 000 SEK, Novel mechanisms in anorexia

Jesper Tegnér received 500 000kr from Hjärnfonden for the project: ”Single Cell Analysis – New window for Stratifying & Targeting Progressive MS” Period: 2016-2017

John Pernow received 1 000 000 SEK from Torsten Söderbergs stiftelse for the project: “Molecular mechanism and novel treatments for cardiovascular complications in diabetes”

Anna Witsap received 100 000 SEK from Njurfonden for the project: “Premature vascular ageing in chronic kidney disease – an epigenetic approach”

Rasmus Gustafsson received 53 000 SEK from Neuroförbundet for the project: “Host genetic influences on antiviral serology in multiple sclerosis”

Linnéa Eriksson has received 360 000 SEK (research months) from the Swedish Heart-Lung Foundation during the period 2016-2017, research project “Improvement of vessel wall healing by glucagonlike peptide-1 after arterial injury and vein grafting in diabetes”.

Ljubica Matic has received 70.000 SEK from Tore Nilsons Stiftelse for the research project “Biomarkers after atherosclerotic plaque instability and stroke; Clinic and experimental studies”.

Silvia Aldi has received 200 000 SEK from Åke Wibergs Stiftelse for the research project “Study of new markers in human carotid Plaque” and 20 000 SEK from Stiftelsen Sigurd and Elsa Goljes Minne .

Ulf Hedin has received 150 000 from Diabetesfonden for the research project “Diabetic vein graft disease”.

Joy Roy has received the Stockholm County Council’s grant for Higher Clinical Researchers of SEK 800 000 over two years for the research project “Abdominal Aortic Aneurysm: New mechanisms and prediction of growth and rupture”

Iva Gunnarsson received a grant from the Swedish Science Council (Distinguished Clinical Researchers) for the project “Systemic Lupus Erythematosus with renal involvement– clinical and histopatological studies” 2016:400 000 SEK 2017:400 000 SEK
Continuation

Magnus Bäck received a grant from the Swedish Science Council (Distinguished Clinical Researchers) for the project: “Arterosclerosis and aortastenosis: A translational study with focus on inflammation and its disintegration”. 2016: 400 000 SEK 2017: 400 000 SEK
Continuation

Jon Lampa received a grant from the Swedish Science Council (Distinguished Clinical Researchers) for the project: “Pain and fatigue in Rheumatoid arthritis – Prevalence, risk factors for widespread pain, and central nervous mechanisms”. 2016: 400 000 SEK 2017: 400 000 SEK
Continuation