Biomimetics – how solutions in nature help us find novel treatment strategies for disease
Speaker: Peter Stenvinkel,
Location: Lecture Hall, CMM L8:00
Host: Martin Schalling
During evolution, many of the more than 2 million animal species that inhabit earth have developed ingenious survival mechanisms that aid in the prevention of obesity, kidney disease, starvation, dehydration and vascular aging, whereas other animals remain susceptible. Understanding why some animals are susceptible to kidney disease while others are protected, using a comparative physiology approach, might provide insights into novel pathways that could be adapted in order to prevent the development of disease in humans. Better understanding of the physiological mechanisms by which felids, bears, seals and the naked mole rat, adapt to certain environments might provide key insights into the mechanisms of human kidney disease and aging. Whereas naked mole rats and seals have developed superior resistance to oxidative stress that protect them under extreme conditions, ingenious mechanisms have during evolution emerged in hibernating bears that protect them from muscle wasting, azotemia and osteoporosis during months of immobilization and anuria.