Asset Publisher

Anca Catrina, Wallenberg Clinical Scholar 2020

Anca Catrina, Wallenberg Clinical Scholar 2020

We congratulate our CMM researcher Professor Anca Catrina, Group Leader at Karolinska Institutet and senior physician, who has been appointed Wallenberg Clinical Scholar 2020. 

Anca Catrina is searching for molecular events that may trigger rheumatoid arthritis. Although more efficient treatments have been developed over the past few years, the treatment response varies largely among patients, and there is no cure or established preventive measure. The identification of disease-triggering factors will help to better explain the molecular mechanisms leading to rheumatoid arthritis and eventually to find better and preventive treatments.

A well-known risk factor is smoking, which changes the structures of proteins in the mucosal membrane in the lungs. These proteins irritate the immune system, likely contributing to the development of a pathogenic systemic autoimmunity long before development of chronic joint inflammation. Some of Anca Catrina’s research topics involve the understanding of the molecular mechanisms and environmental triggers responsible for generation of pathogenic autoimmunity at mucous membranes and its subsequent spreading to the joints.

In this search, Professor Anca Catrina combines molecular investigations with clinical data, including the study of people who present with musculoskeletal complains and already developed autoimmunity and that are therefore at increased risk for developing rheumatoid arthritis, but not yet having the disease. The long-term aim is to enable early-stage identification of these individuals and development of new management strategies and treatments that prevent the immune system from causing chronic damage to the joints. 

Wallenberg Clinical Scholars receive SEK 15 million funding over a five-year period, with the opportunity to extend this for an additional five years.

Press release: https://kaw.wallenberg.org/hon-vill-bota-ledgangsreumatism

NEWS

Ning Xu Landén 2020 year’s winner of the LEO Foundation Award

Ning Xu Landén 2020 year’s winner of the LEO Foundation Award Associate Professor Ning Xu Landén, Group Leader at CMM is the winner of this year’s LEO Foundation Award in Region EMEA...

Nils Landegren receives ERC Starting Grant for studying sex differences in the human immune system

Nils Landegren receives ERC Starting Grant for studying sex differences in the human immune system Photo: Hans Ericksson, SSMF Nils Landegren , Researcher at CMM, has been awarded...

Verification project of SARS-CoV-2 antibody tests receives funding from Swelife

Verification project of SARS-CoV-2 antibody tests receives funding from Swelife Photo: Mattias Bronge, Karolinska Institutet A validation project of new SARS-CoV-2 antibody tests,...

Grant to Qiaolin Deng for the single-cell technology core at CMM

Grant to Qiaolin Deng for the single-cell technology core at CMM Qiaolin Deng, private photo We congratulate Associate Professor and CMM Team Leader Qiaolin Deng who received a SFO...

Identification of key gene for improvement of multiple sclerosis treatments

Identification of key gene for improvement of multiple sclerosis treatments Karl Carlström and Fredirk Piehl. Photo: Stefan Zimmermann   CMM researcher Karl Carlström and...

Sweden’s innovation agency Vinnova extends the funding of Genomic Medicine Sweden with additional SEK 36 million

Sweden’s innovation agency Vinnova extends the funding of Genomic Medicine Sweden with additional SEK 36 million Sweden’s innovation agency Vinnova extends the funding of the national...

The Swedish Heart-Lung Foundation major grant 2020 goes to Marie Wahren-Herlenius

The Swedish Heart-Lung Foundation major grant 2020 goes to Marie Wahren-Herlenius Professor Marie Wahren-Herlenius, Group Leader at CMM, has received the biggest yearly grant in Sweden...

Simple blood test may help predict MS progression, study finds

Simple blood test may help predict MS progression, study finds Photo: Ali Manouchehrinia   A study led by the CMM researchers Ali Manouchehrinia (first...

Experimental study finds new substances with higher specificity and therapeutic potential in multiple sclerosis

Experimental study finds new substances with higher specificity and therapeutic potential in multiple sclerosis   Karl Carlström, photo Stefan Zimmerman   Karl...

Early exposure to cannabis boosts young brains' sensitivity to cocaine, rodent study shows

Early exposure to cannabis boosts young brains' sensitivity to cocaine, rodent study shows A study made by Philippe Melas from Karolinska Institutet together with colleagues at Columbia...