Asset Publisher

CMM researchers hope to be able to replace dysfunctional brain cells

CMM researchers hope to be able to replace dysfunctional brain cells

A new study by CMM researchers supports the theory that replacement of dysfunctional immune cells in the brain has therapeutic potential for neurodegenerative diseases like ALS and Alzheimer’s disease.

The study involved repopulating the brain with new immune cells in an experimental disease model.

- We knew that blood monocytes would infiltrate the CNS in our experimental mouse model, but we did not know to what degree they would adapt to the new microenvironment, says first author Harald Lund to KI News.

- So we dissected the process of repopulation and fully characterised what happened to these cells with time.

 

Professor Robert Harris and Dr. Harald Lund

 

The study is published in Nature Communications.

Read the full news article at KI web site.

NEWS

CMM researchers hope to be able to replace dysfunctional brain cells

CMM researchers hope to be able to replace dysfunctional brain cells
CMM researchers hope to be able to replace dysfunctional brain cells A new study by CMM researchers supports the theory that replacement of dysfunctional immune cells in the brain has...

The vital breathing

The vital breathing
The vital breathing In a radio interview Eric Herlenius, professor in Pediatrics at Karolinska Institutet, discusses what happens when sudden infant death occurs when a small child stops...

New method of identifying biomarkers for unstable arteriosclerosis

New method of identifying biomarkers for unstable arteriosclerosis
New method of identifying biomarkers for unstable arteriosclerosis Atherosclerosis can develop for decades without causing any discomfort, but when the disease becomes unstable, an acute...

Cell publication gives new understanding of how T and B lymphocytes interact in multiple sclerosis

Cell publication gives new understanding of how T and B lymphocytes interact in multiple sclerosis
Cell publication gives new understanding of how T and B lymphocytes interact in multiple sclerosis A study conducted by CMM researcher Faiez al Nimer (shared first author) gives an important...

News Agency Reuters reports about a recent publication by CMM researchers

News Agency Reuters reports about a recent publication by CMM researchers
News Agency Reuters reports about a recent publication by CMM researchers The study suggests that pregnant women with both severe obesity and diabetes may be more likely to have children...

Red blood cells cause cardiovascular injury in type 2 diabetes

Red blood cells cause cardiovascular injury in type 2 diabetes
Red blood cells cause cardiovascular injury in type 2 diabetes Two new studies, conducted at CMM and KI, indicate that harmful effects of substances secreted from red blood cells could...

Mechanism controlling multiple sclerosis risk identified by CMM researchers

Mechanism controlling multiple sclerosis risk identified by CMM researchers
Mechanism controlling multiple sclerosis risk identified by CMM researchers Researchers at CMM have discovered a new mechanism of a major risk gene for multiple sclerosis (MS) that...

CMM researcher Ulf Hedin receives Heart-Lung Foundation’s Great Research Grant 2018

CMM researcher Ulf Hedin receives Heart-Lung Foundation’s Great Research Grant 2018
CMM researcher Ulf Hedin receives Heart-Lung Foundation’s Great Research Grant 2018 The great research grant is awarded annually, and is the largest individual grant by the Heart Lung...

CMM researchers have developed a model of neurogenerative disease

CMM researchers have developed a model of neurogenerative disease
CMM researchers have developed a model of neurogenerative disease The research group Applied Immunology and Immunotherapy at CMM has developed a novel model of neurogenerative disease,...

CMM researcher Louise Sjöholm interviewed for the Food Pharmacy podcast

CMM researcher Louise Sjöholm interviewed for the Food Pharmacy podcast
CMM researcher Louise Sjöholm interviewed for the Food Pharmacy podcast Mia Clase and Lina Nertby Aurell are since 2014 running the popular blog Food Pharmacy about the gut flora, good...