Mechanism controlling multiple sclerosis risk identified by CMM researchers - News
Mechanism controlling multiple sclerosis risk identified by CMM researchers
Researchers at CMM have discovered a new mechanism of a major risk gene for multiple sclerosis (MS) that triggers disease through epigenetic regulation. They also found a protective genetic variant that reduces the risk for MS through the same mechanism.
“We show for the first time that epigenetic mechanisms can cause the disease. In addition, we can connect this mechanism to the genetic variant with the strongest risk for developing MS”, says Maja Jagodic.
The study is published in Nature Communications.
Maja Jagodic and first author Lara Kular.
Photo: Stefan Zimmerman