Asset Publisher

Experimental study finds new substances with higher specificity and therapeutic potential in multiple sclerosis

Experimental study finds new substances with higher specificity and therapeutic potential in multiple sclerosis

 

Karl Carlström, photo Stefan Zimmerman

 

Karl Carlström (first author), Faiez al Nimer and Fredrik Piehl, from CMM (Fredrik Piehl Team), together with coauthors, published a study in which they found a new substance which could potentially be more specific for treating multiple sclerosis (MS) than currently used drugs. Dimethyl fumarate (DMF)/tecfidera is today a leading first-line treatment for relapsing-remitting MS worldwide. The researchers performed an experimental study using animal models, in which they compared DMF to other substances, measuring the protective effect on oligodendrocytes, the cells that are being injured and destroyed in MS.

More details can be found at ki.se (in Swedish). The paper was published in Neurotherapeutics.

NEWS

Sweden’s innovation agency Vinnova extends the funding of Genomic Medicine Sweden with additional SEK 36 million

Sweden’s innovation agency Vinnova extends the funding of Genomic Medicine Sweden with additional SEK 36 million Sweden’s innovation agency Vinnova extends the funding of the national...

The Swedish Heart-Lung Foundation major grant 2020 goes to Marie Wahren-Herlenius

The Swedish Heart-Lung Foundation major grant 2020 goes to Marie Wahren-Herlenius Professor Marie Wahren-Herlenius, Group Leader at CMM, has received the biggest yearly grant in Sweden...

Simple blood test may help predict MS progression, study finds

Simple blood test may help predict MS progression, study finds Photo: Ali Manouchehrinia   A study led by the CMM researchers Ali Manouchehrinia (first...

Experimental study finds new substances with higher specificity and therapeutic potential in multiple sclerosis

Experimental study finds new substances with higher specificity and therapeutic potential in multiple sclerosis   Karl Carlström, photo Stefan Zimmerman   Karl...

Early exposure to cannabis boosts young brains' sensitivity to cocaine, rodent study shows

Early exposure to cannabis boosts young brains' sensitivity to cocaine, rodent study shows A study made by Philippe Melas from Karolinska Institutet together with colleagues at Columbia...

Grant to Eduardo Villablanca for studies of stem cell-mediated tissue regeneration in the intestine

Grant to Eduardo Villablanca for studies of stem cell-mediated tissue regeneration in the intestine Associate Professor Eduardo Villablanca, Group Leader at CMM, has received a Junior...

Anca Catrina, Wallenberg Clinical Scholar 2020

Anca Catrina, Wallenberg Clinical Scholar 2020 We congratulate our CMM researcher Professor Anca Catrina, Group Leader at Karolinska Institutet and senior physician, who has been appointed...

Junior Investigator Award to Carmen Gerlach

Junior Investigator Award to Carmen Gerlach Assistant Professor Carmen Gerlach, Team Leader at CMM, will receive funding during six years from the Swedish Cancer Society (Cancerfonden) for...

Proteins that protect against joint inflammation identified

Proteins that protect against joint inflammation identified " Endogenous proteins that play a vital part in allergies and parasitic infection can prevent the immune system from wrongly...

New study shows that Proprotein Convertase 6 plays a key role in vascular disease

New study shows that Proprotein Convertase 6 plays a key role in vascular disease In a new study published in Circulation Research, researchers at CMM show that the enzyme PCSK6, the...