Unexpected effect of MS drug - News
Unexpected effect of MS drug
Karl Carlström and Fredrik Piehl
Photo: Stefan Zimmerman
Researchers at CMM have studied the mechanism of action of a drug used to treat multiple sclerosis. The results, which are published in the journal Nature Communications, show that the drug affects cells in the innate immune system and that there is an unexpected link between therapeutic effect and an increase in the production of reactive oxygen species.
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Karl E. Carlström, Ewoud Ewing, Mathias Granqvist, Alexandra Gyllenberg, Shahin Aeinehband, Sara Lind Enoksson, Antonio Checa, Tejaswi VS. Badam, Jesse Huang, David Gomez-Cabrero, Mika Gustafsson, Faiez Al Nimer, Craig E. Wheelock, Ingrid Kockum, Tomas Olsson, Maja Jagodic and Fredrik Piehl.
Nature Communications, 12 July 2019. doi:10.1038/s41467-019-11139-3