Non-coding RNAs in inflammatory skin diseases.

Psoriasis is the most common chronic inflammatory skin disease in adults, affecting 2-3% of the population. Psoriasis has a significant impact on patients’ quality of lfe and is now considered as a sytemic disease with significant comorbidities. Our group’s main scientific focus is to explore the role of non-coding regulatory RNAs, including miRNAs and long non-coding RNAs, in psoriasis, to understand their roles in the disease and to explore the possibilities of non-coding RNA modulation for topical and systemic treatment. Another main goal for our research is the identification of miRNA-based biomarkers for prediction of treatment response and diagnosis of comorbidities.a