Francesco Cosentino grupp
The research goal of Prof. Cosentino’s team is to unravel molecular and cellular processes underpinning vascular and cardiac dysfunction in the setting of elevated cardiometabolic risk. The impact of this research is outlined by the notion that prevalence of obesity and type 2 diabetes (T2D) is alarmingly increasing worldwide. Although advances in therapy have reduced morbidity and mortality in T2D, cardiovascular risk is far to be eradicated and mechanism-based therapeutic approaches are in high demand. In this perspective, deciphering novel molecular networks of cardiovascular disease will be instrumental to develop effective diagnostic and therapeutic strategies. Furthermore, the research program also aims to understand the link between environmental factors, metabolic disease and premature cardiovascular aging. These objectives are accomplished by a translational approach focused to characterize cardiovascular phenotypes through novel technologies, genetically engineered animal models and clinical studies.
Francesco Cosentino, MD, PhD
Professor of Cardiology, in the Department of Medicine, Solna, Karolinska Institute and Karolinska University Hospital. Prof. Cosentino is the recipient of grants and prizes from national and international institutions, research councils and private foundations. He is the leading author of more than 120 original articles published in top-ranking, peer-reviewed journals. Prof. Cosentino is member of the Board of the European Society of Cardiology, chairman of the Task Force for 2019 ESC Guidelines on diabetes, pre-diabetes and cardiovascular disease and associate editor of the European Heart Journal.
Circulation and respiration
Aging, Animal models, Cardiovascular, Cell culture, Epigenetics, Flow cytometry, Gene expression, Metabolism, Mitochondria, Oxidative stress, Signal transduction