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Systems metabolism

Systems metabolism

We are a young research group at Karolinska Institutet in Stockholm, Sweden, specializing in detailed analyses of cellular metabolism using modern measurement techniques and mathematical models. Our work aims for a deeper and more quantitative understanding of how various cell types in the human body process nutrients to harvest energy and synthesize macromolecules. In particular, we are interested in the metabolic derangements that occur in cancer cells, but also in specialized modes metabolism unique to other cell types.

Our work involves large-scale data integration, mathematical models of metabolism, transcriptomics, mass-spectrometry based metabolite profiling, and cellular physiology. We are working in close collaboration with colleagues at the University of California, San Diego, as well as Harvard University and the Broad Institute (Boston).

Link to our web page.

 

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Group leader

Roland Nilsson

E-mail

roland.nilsson@ki.se

Job title

Assistant professor

House

L5:02

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Research

Bioinformatics, Endocrinology and metabolism, Haematology, Metabolomics

Disease

Cancer

Competence/titles

Biochemistry, Metabolism