Selected publications

Selected publications

Eken S, Jin H, Chernogubova E, Li Y, Simon N, Sun C, et alMicroRNA-210 Enhances Fibrous Cap Stability in Advanced Atherosclerotic Lesions. Circ. Res. 2017 Feb;120(4):633-644.

Hartmann D, Fiedler J, Sonnenschein K, Just A, Pfanne A, Zimmer K, et al. MicroRNA-Based Therapy of GATA2-Deficient Vascular Disease. Circulation. 2016 Dec;134(24):1973-1990.

Stellos K, Gatsiou A, Stamatelopoulos K, Perisic Matic L, John D, Lunella F, et al. Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation. Nat. Med. 2016 Oct;22(10):1140-1150.

Kojima Y, Volkmer J, McKenna K, Civelek M, Lusis A, Miller C, et al. CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis. Nature. 2016 Aug 4;536(7614):86-90.

Wang D, Deuse T, Stubbendorff M, Chernogubova E, Erben R, Eken S, et alLocal MicroRNA Modulation Using a Novel Anti-miR-21-Eluting Stent Effectively Prevents Experimental In-Stent Restenosis. Arterioscler. Thromb. Vasc. Biol. 2015 Sep;35(9):1945-53.

Maegdefessel L, Dalman R, Tsao P. Pathogenesis of abdominal aortic aneurysms: microRNAs, proteases, genetic associations. Annu. Rev. Med. 2014;65:49-62.

Maegdefessel L, Spin J, Raaz U, Eken S, Toh R, Azuma J, et al. miR-24 limits aortic vascular inflammation and murine abdominal aneurysm development. Nat Commun. 2014 Oct 31;5:5214.

Deuse T, Hua X, Wang D, Maegdefessel L, Heeren J, Scheja L, et al. Dichloroacetate prevents restenosis in preclinical animal models of vessel injury. Nature. 2014 May;509(7502):641-4.

Maegdefessel L. The emerging role of microRNAs in cardiovascular disease. J. Intern. Med. 2014 Dec;276(6):633-44.

Maegdefessel L, Azuma J, Toh R, Deng A, Merk D, Raiesdana A, et al. MicroRNA-21 blocks abdominal aortic aneurysm development and nicotine-augmented expansion. Sci Transl Med 2012 Feb;4(122):122ra22.

Maegdefessel L, Azuma J, Toh R, Merk D, Deng A, Chin J, et al. Inhibition of microRNA-29b reduces murine abdominal aortic aneurysm development. J. Clin. Invest. 2012 Feb;122(2):497-506.