Selected publications

Selected publications

Lundbäck P, Lea JD, Sowinska A, Ottosson L, Fürst CM, Steen J, Aulin C, Clarke JI, Kipar A, Klevenvall L, Yang H, Palmblad K, Park BK, Tracey KJ, Blom AM, Andersson U, Antoine DJ, Erlandsson Harris H. A novel high mobiliy group box 1 neutralizing chimeric antibody attenuates drug-induced liver injury and postinjury inflammation in miceHepatology. 2016 Nov;64(5):1699-1710. Epub 2016 Sep 1.

Aulin C, Lundbäck P, Palmblad K, Klareskog L, Erlandsson Harris H. An in vivo cross-linkable hyaluronan gel with inherent anti-inflammatory properities reduced OA cartilage destruction in female mice subjected to cruciate ligament transection. Osteoarthritis Cartilage. 2017 Jan;25(1):157-165. Epub 2016 Aug 29.

Assadi G, Saleh R, Hadizadeh F, Vesterlund L, Bonfiglio F, Halfvarson J, Törkvist L, Eriksson AS, Harris HE, Sundberg E, D'Amato M. LACC1 polymorphisms in inflammatory bowel disease and juvenile idiopathic arthritis. Genes Immun. 2016 Jun;17(4):261-4. Epub 2016 Apr 21.

Lundbäck P, Stridh P, Klevenvall L, Jenkins RE, Fischer M, Sundberg E, Andersson U, Antoine DJ, Harris HE. Characterisation of the inflamamtory properties of actively released HMGB1 in Juvenile Idiopathic Arthritis.  Antioxid Redox Signal. 2016 Apr 20;24(12):605-19. Epub 2015 Feb 6.

Palmblad K, Schierbeck H, Sundberg E, Horne AC, Harris HE, Henter JI, Antoine DJ, Andersson U. High systemic levels of the cytokine-inducing HMGB1 isoform secreted in severe macrophage activation syndrome. Mol Med. 2015 Jan 27;20:538-47. 

Nyström S, Antoine DJ, Lundbäck P, Lock JG, Nita AF, Högstrand K, Grandien A, Erlandsson-Harris H, Andersson U, Applequist SE. TLR4 activation regulates damage-associated molecular pattern isoforms released during pyroptotic cell deathEMBO J. 2013 Jan 9;32(1):86-99.

Lu B, Nakamura T, Inouye K, Li J, Tang Y, Lundbäck P, Valdes-Ferrer SI, Olofsson PS, Kalb T, Roth J, Zou Y, Erlandsson-Harris H, Yang H, Ting J P-Y, Wang H, Andersson U, Antoine DJ, Chavan SS, Hotamisligil GS, Tracey KJ. Novel role of PKP in inflammasome activation and HMGB1 releaseNature. 2012 Aug 30;488(7413):670-4.

Hreggvidsdóttir HS, Lundberg AM, Aveberger AC, Klevenvall L, Andersson U, Harris HE. High Mobility group box protein 1 (HMGB1)-partner molecule complexes enhance cytokine production by signalling through the partner molecule receptor. Mol Med. 2012 Mar 27;18:224-30. 

Yang H, Hreggvidsdottir HS, Palmblad K, Wang H, Ochani M, Li J, Lu B, Chavan S, Rosas-Ballina M, Alabed Y, Akira S, Bierhaus A, Erlandsson-Harris H, Andersson U, Tracey KJ. A critical cysteine is required for HMGB1 binding to TLR4 and activation of macrophage cytokine release.  Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):11942-7.

Kokkola R, Sundberg E, Ulfgren AK, Palmblad K, Li J, Wang H, Ulloa L, Yang H, Yan XJ, Furie R, Chiorazzi N, Tracey KJ, Andersson U, Erlandsson Harris H. High Mobility group box chromosomal protein 1 (HMGB1): A novel proinflammatory mediator in synovitis.  Arthritis Rheum. 2002 Oct;46(10):2598-603.