Selected publications

Selected publications

Sandgren K, Smed-Sörensen A, Forsell M, Soldemo M, Adams W, Liang F, Perbeck L, Koup RA, Wyatt RT, Karlsson Hedestam GB, Loré K. Human plasmacytoid dendritic cells efficiently capture HIV-1 envelope glycoproteins via CD4 for antigen presentation. J. Immunol. 2013 Jul;191(1):60-9.

Liang F, Bond E, Sandgren K, Smed-Sörensen A, Rangaka M, Lange C, Koup RA, McComsey GA, Lederman MM, Wilkinson RJ, Andersson J, Loré K. Dendritic cell recruitment in response to skin antigen tests in HIV-1-infected individuals correlates with the level of T-cell infiltration. AIDS 2013 Apr;27(7):1071-80.

Adams W, Berenson R, Karlsson Hedestam G, Lieber A, Koup R, Loré K. Attenuation of CD4+ T-cell function by human adenovirus type 35 is mediated by the knob protein. J. Gen. Virol. 2012 Jun;93(Pt 6):1339-44.

Bond E, Liang F, Sandgren K, Smed-Sörensen A, Bergman P, Brighenti S, Adams WC, Betemariam SA, Rangaka MX, Lange C, Wilkinson RJ, Andersson J, Loré K. Plasmacytoid dendritic cells infiltrate the skin in positive tuberculin skin test indurations. J. Invest. Dermatol. 2012 Jan;132(1):114-23.

Smed-Sörensen A, Loré K. Dendritic cells at the interface of innate and adaptive immunity to HIV-1. Curr Opin HIV AIDS 2011 Sep;6(5):405-10.

Gujer C, Sandgren KJ, Douagi I, Adams WC, Sundling C, Smed-Sörensen A, Seder RA, Karlsson Hedestam GB, Loré K. IFN-α produced by human plasmacytoid dendritic cells enhances T cell-dependent naïve B cell differentiation. J. Leukoc. Biol. 2011 Jun;89(6):811-21.

Adams WC, Gujer C, McInerney G, Gall JG, Petrovas C, Karlsson Hedestam GB, Koup RA, Loré K. Adenovirus type-35 vectors block human CD4+ T-cell activation via CD46 ligation. Proc. Natl. Acad. Sci. U.S.A. 2011 May;108(18):7499-504.

Sundling C, O’Dell S, Douagi I, Forsell MN, Mörner A, Loré K, Mascola JR, Wyatt RT, Karlsson Hedestam GB. Immunization with wild-type or CD4-binding-defective HIV-1 Env trimers reduces viremia equivalently following heterologous challenge with simian-human immunodeficiency virus. J. Virol. 2010 Sep;84(18):9086-95.

Sundling C, Forsell M, O’Dell S, Feng Y, Chakrabarti B, Rao S, Loré K, Mascola JR, Wyatt RT, Douagi I, Karlsson Hedestam GB. Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates. J. Exp. Med. 2010 Aug;207(9):2003-17.

Douagi I, Forsell MN, Sundling C, O’Dell S, Feng Y, Dosenovic P, Li Y, Seder R, Loré K, Mascola JR, Wyatt RT, Karlsson Hedestam GB. Influence of novel CD4 binding-defective HIV-1 envelope glycoprotein immunogens on neutralizing antibody and T-cell responses in nonhuman primates. J. Virol. 2010 Feb;84(4):1683-95.

Loré K, Karlsson Hedestam G. Novel adjuvants for B cell immune responses.  Curr Opin HIV AIDS 2009 Sep;4(5):441-6.

Bond E, Adams WC, Smed-Sörensen A, Sandgren KJ, Perbeck L, Hofmann A, Andersson J, Loré K. Techniques for time-efficient isolation of human skin dendritic cell subsets and assessment of their antigen uptake capacity. J. Immunol. Methods 2009 Aug;348(1-2):42-56.

Adams WC, Bond E, Havenga MJ, Holterman L, Goudsmit J, Karlsson Hedestam GB, Koup RA, Loré K. Adenovirus serotype 5 infects human dendritic cells via a coxsackievirus-adenovirus receptor-independent receptor pathway mediated by lactoferrin and DC-SIGN. J. Gen. Virol. 2009 Jul;90(Pt 7):1600-10.

Douagi I, Gujer C, Sundling C, Adams WC, Smed-Sörensen A, Seder RA, Karlsson Hedestam GB, Loré K. Human B cell responses to TLR ligands are differentially modulated by myeloid and plasmacytoid dendritic cells. J. Immunol. 2009 Feb;182(4):1991-2001.

Loré K, Adams WC, Havenga MJ, Precopio ML, Holterman L, Goudsmit J, Koup RA. Myeloid and plasmacytoid dendritic cells are susceptible to recombinant adenovirus vectors and stimulate polyfunctional memory T cell responses. J. Immunol. 2007 Aug;179(3):1721-9.